Medical Cannabis for Multiple Sclerosis: Treatments & UK Use

Alternaleaf Team
Written by
Alternaleaf Team
Jun 10, 2025
Last updated:
Jun 10, 2025

Multiple sclerosis (MS) is a condition that affects the brain and spinal cord. Some of the common symptoms of multiple sclerosis include: 

  • Feeling extremely tired (fatigue)
  • Problems with your eyes or your vision
  • Numbness tingling 
  • Feeling off balance or dizzy
  • Muscle cramps, spasms and stiffness
  • Problems with memory or concentration

Symptoms can appear suddenly - this is known as a flare-up - and can get worse over time. 

Currently, there is no cure, but different treatment options are available to help manage symptoms. And one of those potential options is medical cannabis. Since 2018, medical cannabis has been legally available on prescription through licensed clinics like Alternaleaf for 50+ conditions. You can find out if you’re eligible by completing the quick questionnaire on our website.

Below we’ll be exploring the possible benefits of medical cannabis for MS patients, different ways to consume and potential side effects. 

Can Medical Cannabis Help with Multiple Sclerosis Symptoms?

The endocannabinoid system, or the ECS, is a messenger and receptor system that is integral to homeostasis (the management of balance) within the human body. The ECS influences and modulates pretty much every single function within your body, directing, correcting and managing your overall health. 

One of the core components of the ECS are the cannabinoid receptors, which includes CB1 and CB2. They’re one of the main reasons behind why medical cannabis works so positively on so many different conditions. Many experts believe that, by consuming compounds found in the plant, it’s possible to interact with these receptors in the body, and ease symptoms of conditions like MS.

Various studies support the claim that medical cannabis is an effective anti-inflammatory, and has the potential to ease symptoms of multiple sclerosis, for example reducing pain and muscle stiffness. Put very simply, medical cannabis works by harnessing cannabinoids to bind to pain receptors and nerve cells, then slow down the pain response. This, in turn, eases discomfort.

But let's break things down a little more. 

Benefits of CBD and THC for MS

Tetrahydrocannabinolis (THC) and cannabidiol (CBD) are two of over 100 cannabinoids found in the cannabis plant. They’re active compounds that can cause effects throughout the body, and you’ll see them often when researching medical cannabis. The main difference is that THC can produce a ‘high’, while CBD doesn’t. And remember, whilst there is evidence to give a general idea of how both THC and CBD may react with the body, they can affect every individual differently. 

It’s possible that CBD is an effective option for nerve pain, having the potential to reduce inflammation, support nerve repair and improve circulation. 

When THC binds to the CB1 receptors, it can affect appetite and pain as well as aid in relaxation. 

Although there’s evidence above of how THC and CBD have the potential to help ease some of the symptoms of MS, these two compounds can sometimes be greater together. This is due to a phenomenon known as the entourage effect.

Best Ways to Consume Medical Cannabis for Multiple Sclerosis 

When it comes to medical cannabis, the way you consume is down to personal preference, lifestyle and your clinicians recommendation. They’ll advise you on how to consume based on your symptoms and condition, but they’ll also work with you to find what you’re comfortable with. Remember, you may not choose the right form at first, so speak to your clinician if you have any questions or feedback. If you aren’t getting on with a particular form, your clinician may be able to recommend an alternative. Below we’ve got a brief explanation of different ways to consume medical cannabis:  

  • Inhaling: This method of consumption provides rapid onset of effects, typically within minutes, making it suitable for immediate relief of symptoms such as pain. However, remember that smoking your prescription is illegal in the UK and could lead to lung damage. So, if your preferred method is inhalation, purchasing a dry herb vaporiser through a licensed clinic like Alternaleaf is the best solution.
  • Cannabis Edibles & Capsules: Consuming cannabis-infused ‘edibles’, like pastilles, or soft gel capsules, results in slower onset of effects, which can take between 1 to 2 hours. This method is ideal for longer-lasting relief.
  • CBD & THC Oils/Tinctures: Placing cannabis oil or tincture under the tongue provides a faster onset than edibles, usually within 15 to 30 minutes, and, like edible options, relief tends to last. 

Sativex NHS coverage

The NHS supports Sativex for treating MS spasticity. Sativex is a cannabis-based medicine that is sprayed into the mouth, and contains both THC and CBD. However, it’s the only cannabis-based MS treatment in the UK that is approved, and therefore possibly available, through the NHS. 

It can take much longer to get a medical cannabis prescription through the NHS, and even then it’s very rare they prescribe. So, if you want a more reliable and accessible option, we recommend exploring a private clinic like Alternaleaf. They have many more medication options, and prescribe for over 50 conditions. 

Is Medical Cannabis Safe for Multiple Sclerosis Patients?

Most common side effects are short-term, and should wear off within a few hours. These include:

  • Coughing (when using an inhalable form)                   
  • Bloodshot or irritated eyes      
  • Increased appetite             
  • Dry mouth or thirst             
  • Dizziness or loss of balance 
  • Nausea 
  • Feeling tired 

Most of the above shouldn’t cause you any concern. However, if you experience any debilitating side effects, and if they persist, stop taking your medication immediately, and speak to your clinician.

The best way to avoid side effects is to follow the dosage guidance your clinician gives you. They’ll work with you to choose a dosage that suits you and your symptoms. You may not get it right the first time you use medical cannabis, which is why we recommend starting slow. It’s also important to remember that everyone’s body can react differently, and you’ll have your own individual tolerance to the medication. Just monitor how you react to your medication, and feed this back to your clinician during your next appointment. 

Also keep in mind that medical cannabis could potentially interact with other medications. If you are prescribed other medication for MS, it’s best to speak to your Doctor or clinician before consuming any medical cannabis. 

Can cannabis slow Multiple Sclerosis progression?

We mentioned above that there is no known cure for MS. And the same goes for slowing the progression of the condition. There are only treatments that will help manage the symptoms, one of those being medical cannabis. 

So whilst medical cannabis for MS fatigue relief or inflammation and pain is a possibility, there’s no evidence to suggest it will stop the progression of the condition. But as always, we’re hopeful that more research will be conducted on this incredible plant to fully understand its true potential.

Summary

There’s some evidence that shows the potential benefits of medical cannabis, THC and/or CBD oil for MS patients in the UK and the rest of the world. However, one thing is clear: more research is needed. It’s why at Alternaleaf, we’re trying to push medical cannabis into the mainstream, acting as pioneers for our patients. It has the potential to help - so let’s get it there. 

The best thing to do is speak to your Doctor or clinician, or seek the help of a licensed medical cannabis clinic like Alternaleaf if you’re considering medical cannabis treatment. Find out if you’re eligible by heading to our website and completing our 30 second questionnaire.